十全大补汤联合常规早期肠内营养对肺癌切除术后患者免疫功能及临床疗效的影响(1)
摘要 目的：探究十全大补汤联合常规早期肠内营养对肺癌切除术后患者免疫功能及临床疗效影响，为临床肺癌患者的治疗方案提供选择。方法：选取2016年12月至2018年4月辽宁中医药大学附属第二医院收治的肺癌切除术患者97例作为研究对象，按照就诊顺序编号，采用随机数字表法分为对照组(n=48)和观察组(n=49)，对照组早期肠内营养支持，观察组辅助十全大补汤，2组均连续治疗4周。比较2组患者入组时、治疗2周后、4周后在免疫功能(包括CD3+、CD4+、CD8+、IgA、IgM、IgG)和生命质量(包括生理、社会/家庭、情感、功能)、中医证候积分(包括乏力、胸痛、心悸气短)指标变化情况。结果：2组患者治疗前CD3+、CD4+、CD8+、IgA、IgM、IgG、乏力、胸痛、心悸气短、生理、社会/家庭、情感、功能比较，差异无统计学意义(P>0.05)。治疗2周、4周后，2组患者上述指标均较治疗前明显改善，且观察组上述指标均明显优于对照组(P<0.05)。治疗4周后观察组显效率、总有效率显著优于对照组(P<0.05)。结论：十全大补汤联合常规早期肠内营养能提高肺癌切除术后患者免疫功能，改善生命质量，提高疗效，具有较高的临床应用价值。
關键词 十全大补汤;早期肠内营养;肺癌切除术;免疫功能;临床症状;生命质量;临床疗效
Effects of Shiquan Dabu Decoction Combined with Routine Enteral Nutrition on Immune Function and Clinical Efficacy in Patients After Lung Cancer Resection
Feng Xiaofei，Yang Zhe，Suo Fengru，Song Wenjie
(Oncology Department，The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine/Liaoning Institute of Traditional Chinese Medicine，Shenyang 110034，China)
Abstract Objective：To explore effects of Shiquan Dabu Decoction combined with conventional early enteral nutrition on immune function and clinical efficacy in patients after lung cancer resection，and to provide a choice for clinical treatment in patients with lung cancer.Methods：A total of 97 patients after lung cancer resection treated in our hospital from December 2016 to April 2018 were randomly divided into control group(n=48)and observation group(n=49)according to the order of admission.The control group was treated with early enteral nutrition support，while the observation group was also assisted with Shiquan Dabu Decoction，and the 2 groups were treated for 4 weeks continuously.Index changes of immune function(including CD3+，CD4+，CD8+，IgA，IgM and IgG)，quality of life(including physiology，society / family，emotion and function)and syndrome scores in traditional Chinese medicine(TCM)(including fatigue，chest pain，palpitation and short of breath)were compared between the 2 groups of patients when they entered the groups，as well as 2 weeks and 4 weeks after the treatment.Results：Before the treatment，there was no significant difference between the 2 groups in the CD3+，CD4+，CD8+，IgA，IgM，IgG，fatigue，chest pain，palpitation，short of breath，physiology，society / family，emotion and function(P>0.05).After 2 weeks and 4 weeks of the treatment，the above indexes of the 2 groups were significantly improved compared with those before the treatment，and the above indexes in the observation group were significantly better than those in the control group(P<0.05).After 4 weeks of the treatment，the effective rate and total effective rate in the observation group were significantly better than those in the control group(P<0.05).Conclusion：The combination of Shiquan Dabu Decoction and routine early enteral nutrition can improve the immune function of patients after lung cancer resection，improve the quality of life and improve the efficacy.It has high value in clinical practice., 百拇医药(冯晓飞 杨哲 索凤茹 宋文杰)
關键词 十全大补汤;早期肠内营养;肺癌切除术;免疫功能;临床症状;生命质量;临床疗效
Effects of Shiquan Dabu Decoction Combined with Routine Enteral Nutrition on Immune Function and Clinical Efficacy in Patients After Lung Cancer Resection
Feng Xiaofei，Yang Zhe，Suo Fengru，Song Wenjie
(Oncology Department，The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine/Liaoning Institute of Traditional Chinese Medicine，Shenyang 110034，China)
Abstract Objective：To explore effects of Shiquan Dabu Decoction combined with conventional early enteral nutrition on immune function and clinical efficacy in patients after lung cancer resection，and to provide a choice for clinical treatment in patients with lung cancer.Methods：A total of 97 patients after lung cancer resection treated in our hospital from December 2016 to April 2018 were randomly divided into control group(n=48)and observation group(n=49)according to the order of admission.The control group was treated with early enteral nutrition support，while the observation group was also assisted with Shiquan Dabu Decoction，and the 2 groups were treated for 4 weeks continuously.Index changes of immune function(including CD3+，CD4+，CD8+，IgA，IgM and IgG)，quality of life(including physiology，society / family，emotion and function)and syndrome scores in traditional Chinese medicine(TCM)(including fatigue，chest pain，palpitation and short of breath)were compared between the 2 groups of patients when they entered the groups，as well as 2 weeks and 4 weeks after the treatment.Results：Before the treatment，there was no significant difference between the 2 groups in the CD3+，CD4+，CD8+，IgA，IgM，IgG，fatigue，chest pain，palpitation，short of breath，physiology，society / family，emotion and function(P>0.05).After 2 weeks and 4 weeks of the treatment，the above indexes of the 2 groups were significantly improved compared with those before the treatment，and the above indexes in the observation group were significantly better than those in the control group(P<0.05).After 4 weeks of the treatment，the effective rate and total effective rate in the observation group were significantly better than those in the control group(P<0.05).Conclusion：The combination of Shiquan Dabu Decoction and routine early enteral nutrition can improve the immune function of patients after lung cancer resection，improve the quality of life and improve the efficacy.It has high value in clinical practice., 百拇医药(冯晓飞 杨哲 索凤茹 宋文杰)
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